myanatomy
Your space to understand the human body
Local-first learningFind a conceptY
Thorax

Heart, Pericardium and Great Vessels

Place the heart within its pericardial sac and identify the major vessels connecting to it.

An oblique organ in the central chest

The heart lies within the middle mediastinum, behind the sternum and between the lungs. It is not entirely on the left: a substantial portion lies near or to the right of the midline. Its pointed apex usually faces downwards, forwards and towards the left, while its broader base faces mainly backwards. The right ventricle forms much of the anterior surface, and the left atrium contributes much of the posterior base. These relationships help translate a familiar four-chamber diagram into the body’s three-dimensional arrangement.

SEE THE CONNECTIONTap a label to explore

Heart surface to surrounding sac

Heart surface to surrounding sac. Heart wall: Contracting organ tissue. Visceral serous pericardium: Epicardium closely covers the heart. Pericardial cavity: Small lubricating fluid layer. Parietal serous and fibrous pericardium: Outer supporting sacOpen diagram larger ↗
Schematic layer order from heart outwards; the normal fluid space is very thin.

A sac that permits movement

The pericardium surrounds the heart and the roots of its major vessels. Its fibrous outer component helps support position, while serous layers provide smooth surfaces. The visceral serous layer closely covers the heart and is also called the . A small amount of fluid normally lies between visceral and parietal serous layers, reducing friction as the heart moves. The heart is not floating inside a large fluid-filled chamber. Excess fluid can become important if it raises surrounding pressure enough to impair filling, depending partly on how quickly it accumulates.

Connections at the top and back

The aorta carries blood from the left ventricle into the systemic circulation. The leaves the right ventricle and divides towards the lungs. Superior and inferior venae cavae return systemic blood to the right atrium, while pulmonary veins return oxygenated blood to the left atrium. These great vessels anchor the organ while allowing rhythmic motion. Coronary vessels serve the heart muscle itself rather than replacing these main inflow and outflow routes. Regional anatomy combines chamber orientation, the surrounding sac and vessel connections into one coherent map of the beating heart.

BUILD YOUR MEDICAL VOCABULARY

Key terms

Apex of the heart
The pointed region usually directed downwards, forwards and leftwards.
Epicardium
The visceral serous pericardial layer covering the heart surface.
Pulmonary trunk
The large artery carrying blood from the right ventricle towards the lungs.
Vena cava
A major vein returning systemic blood to the right atrium.
Explore all terms →

MAKE THE CONNECTIONS STICK

A quick check-in

3 questions. Take your time. Mistakes help you learn.

Sources & further reading

Original MyAnatomy explanation and schematic · Source review: 26 October 2026 · Foundational education. See editorial standards and review limits.

KEY TERM

Explore the glossary →